Understanding how viruses interact with mitochondrial functions
Evolution-guided Studies of Mitochondrial Functions
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10881889
This study looks at how viruses affect the tiny powerhouses in our cells called mitochondria, aiming to find new ways to understand our immune responses and discover potential treatments that could help patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10881889 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between viruses and mitochondrial functions to uncover new gene functions and cellular processes. By studying how infections affect cellular responses, the research aims to identify key regulators involved in these processes, such as the P53 protein. The approach combines genomic analysis with cell-based assays to explore the effects of viral infections on mitochondria, ultimately leading to the development of a user-friendly database for researchers. Patients may benefit from insights gained about immune responses and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with autoimmune diseases or conditions related to mitochondrial dysfunction.
Not a fit: Patients with non-viral related conditions or those not affected by mitochondrial issues may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases linked to mitochondrial dysfunction and viral infections.
How similar studies have performed: Previous research has shown promise in understanding host-virus interactions, suggesting that this approach could yield significant insights.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HANCKS, DUSTIN — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: HANCKS, DUSTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases