Understanding how uncertainty affects mental health
Quantifying the cognitive processes supporting computations of stochasticity and volatility in humans
This study is looking at how people with anxiety and schizophrenia think about uncertainty, by seeing how their brains react to different kinds of confusing information, and it aims to help us understand these feelings better so we can find better ways to support those who experience them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10843239 on NIH RePORTER |
What this research studies
This research investigates the cognitive processes that contribute to feelings of uncertainty in individuals with mental health disorders such as anxiety and schizophrenia. By examining how the brain processes different types of noise in observations, the study aims to identify specific computational mechanisms that may lead to cognitive dysfunctions. Participants will engage in a novel task designed to assess their responses to varying levels of uncertainty over time, providing insights into how these processes can differ among individuals. The findings could help clarify the relationship between uncertainty and mental illness, potentially leading to improved treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing anxiety disorders or other mental health issues related to uncertainty.
Not a fit: Patients with stable mental health and no history of anxiety or related disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals suffering from anxiety and other mental health disorders.
How similar studies have performed: Previous research has shown promising results in understanding cognitive processes related to uncertainty, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Piray, Payam — University of Southern California
- Study coordinator: Piray, Payam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.