Understanding how the thalamus affects cognitive control in the brain

Cognitive Control Functions of the Human Thalamus

NIH-funded research University of Iowa · NIH-10778187

This study is looking at how a part of the brain called the thalamus helps control thinking and behavior, especially in people with conditions like schizophrenia and ADHD, to better understand how problems in this area might affect mental health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10778187 on NIH RePORTER

What this research studies

This research investigates the role of the human thalamus in cognitive control, which is essential for regulating behaviors and mental processes. It focuses on how the thalamus interacts with other brain regions to influence cognitive functions, particularly in patients with neurological and psychiatric disorders like schizophrenia and ADHD. By using advanced techniques to analyze brain activity, the study aims to uncover how thalamic dysfunction impacts cognitive control and overall mental health.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with neurological or psychiatric disorders that affect cognitive control, such as schizophrenia, ADHD, or those recovering from traumatic brain injuries.

Not a fit: Patients without cognitive control impairments or those with conditions unrelated to thalamic function may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for cognitive impairments associated with various mental health disorders.

How similar studies have performed: While the role of the thalamus in cognitive control is increasingly recognized, this specific investigation into its functions in humans is relatively novel and has not been extensively tested.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.