Understanding how the structure of brain neurons affects their function
Integrated functional and structural analysis of an entire column in mouse primary visual cortex
This study is looking at how the way brain cells are organized in the mouse's vision area affects how they work, using special imaging tools to gather detailed information, which could help us learn more about brain connections and their impact on mental health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10505417 on NIH RePORTER |
What this research studies
This research investigates the relationship between the structural organization of neurons in the mouse primary visual cortex and their functional properties. By utilizing advanced imaging techniques like electron microscopy and calcium imaging, the study aims to generate large-scale anatomical and functional measurements. The researchers will integrate these datasets using machine learning models to better understand how the brain's structure influences its function. This approach could lead to new insights into brain connectivity and its implications for mental health disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with neurological or psychiatric disorders.
Not a fit: Patients with conditions unrelated to brain structure or function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain function and potentially lead to improved treatments for mental health disorders.
How similar studies have performed: Other research has shown promise in using machine learning to model brain function, indicating that this approach could yield significant insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Abbasi Asl, Reza — University of California, San Francisco
- Study coordinator: Abbasi Asl, Reza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.