NIH-funded research R01 grant

Understanding how the retina processes information with advanced AI models

Official title: CRCNS Research Proposal: Optimal Information processing via cell types

Funded at New York University · NIH-11538397 · Data updated 2026-11-12

A NIH-funded project uses smart computer models to explain why the human retina has many cell types and how they help vision.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 30, 2026
Project endSeptember 29, 2030
Funding year2026
Award (this year)$1,220,425
NIH project number1R01EY040100-01
Project IDNIH-11538397 on NIH RePORTER

Who could benefit from this research

Could help

Not a patient-facing study; this is a basic science project using retinal data and animal/arena measurements.

Less likely to help

There is no direct patient trial or treatment in this grant.

What this research studies

Researchers at New York University will use modern machine learning to build flexible models of retinal information processing. By comparing model predictions with measurements from primate and squirrel retinas, they aim to connect general information-processing principles with the function of specific retinal cell types. The work looks at color channels, realistic noise, and the diverse retinal cell mosaic to uncover why the eye is so complex yet efficient at vision.

Why it matters

Potential benefit: If successful, this work could deepen our understanding of vision and guide future therapies or artificial vision technologies.

How similar studies have gone: Previous EC-based retina models captured only a subset of cell-type diversity; this project aims to expand that understanding with more realistic modeling.

Where this research is happening

  • New York University
    New York, United States
    Active

Researchers

  • Principal investigator: Pearson, John — New York University
  • Study coordinator: Pearson, John

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.