NIH-funded research R01 grant

Understanding how the microbiome affects cancer development and treatment

Official title: Exploiting Public Metagenomic Data to Uncover Cancer-Microbiome Relationships

Funded at Graduate School of Public Health and Health Policy · NIH-10990882 · Data updated 2026-11-12

This study is looking at how the tiny germs in our bodies might affect cancer growth and how well treatments like immunotherapy work, so that patients can better understand how their own germs could influence their cancer care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGraduate School of Public Health and Health Policy
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 1, 2019
Project endAugust 31, 2029
Funding year2024
Award (this year)$427,476
NIH project number2R01CA230551-06
Project IDNIH-10990882 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with various types of cancer, particularly those undergoing immunotherapy.

Less likely to help

Patients with non-cancerous conditions or those not undergoing any form of treatment may not receive direct benefits from this research.

What this research studies

This research investigates the relationship between the microbiome and cancer, focusing on how changes in microbial communities may influence cancer progression and response to treatments like immunotherapy. By creating and enhancing databases that compile public microbiome data, the project aims to facilitate the analysis of microbial signatures associated with various cancers. Patients may benefit from improved understanding of how their microbiome could affect their cancer treatment outcomes. The research employs advanced data curation and analysis techniques to ensure high-quality, accessible information for further studies.

Why it matters

Potential benefit: If successful, this research could lead to personalized cancer treatments based on individual microbiome profiles.

How similar studies have gone: Previous research has shown promising results in understanding the microbiome's role in cancer, indicating that this approach could yield valuable insights.

Where this research is happening

  • Graduate School of Public Health and Health Policy
    New York, United States
    Active

Researchers

  • Principal investigator: Waldron, Levi — Graduate School of Public Health and Health Policy
  • Study coordinator: Waldron, Levi

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.