Understanding how the lung responds to injury and infection
Immunobiology of the normal and injured lung
This study is looking at how healthy lungs work and how they react to injuries like ARDS, with the goal of finding better treatments for people with serious lung problems, especially those affected by COVID-19.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11017724 on NIH RePORTER |
What this research studies
This research investigates the complex biology of the lung, particularly how it functions normally and how it responds to injuries such as acute lung injury and acute respiratory distress syndrome (ARDS). By utilizing advanced imaging techniques and studying various immune cells, the research aims to uncover the mechanisms behind lung injury and the role of blood components like platelets and neutrophils. The findings could lead to new therapeutic strategies to improve outcomes for patients suffering from severe lung conditions, especially in the context of challenges posed by COVID-19.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old who are experiencing or at risk for acute lung injury or ARDS.
Not a fit: Patients with chronic lung conditions or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve recovery and outcomes for patients with acute lung injuries.
How similar studies have performed: Previous research has shown promise in understanding lung biology and immune responses, indicating that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Looney, Mark Roberts — University of California, San Francisco
- Study coordinator: Looney, Mark Roberts
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.