Understanding how the human amygdala processes smells

Characterizing the primary olfactory subregions of the human amygdala

NIH-funded research Northwestern University at Chicago · NIH-11009958

This study is exploring how the part of your brain that processes smells connects to the area that handles emotions, to better understand how our sense of smell influences our feelings and social interactions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11009958 on NIH RePORTER

What this research studies

This research investigates the connections between the olfactory bulb and the human amygdala, focusing on how these connections influence behavior related to smell. By using advanced imaging techniques and electrical stimulation, the study aims to map the anatomical and functional properties of these olfactory pathways. This research is particularly important because existing knowledge is largely based on animal studies, which may not fully apply to humans. The findings could provide insights into how smell affects emotions and social interactions in people.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in understanding the relationship between smell and emotional responses, particularly those with anxiety disorders.

Not a fit: Patients who do not have any olfactory processing issues or emotional disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of how olfactory processing impacts emotional and social behaviors, potentially leading to new treatments for anxiety disorders and other related conditions.

How similar studies have performed: While there have been successful studies on olfactory processing in animals, this research is novel as it focuses specifically on human olfactory pathways and their implications for behavior.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.