Understanding how the brain processes pain in chronic pain conditions
Investigating neural mechanisms of hypersensitivity in chronic pain
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10904661
This study is looking at how the brain processes pain in people with ongoing pain conditions to understand why they feel more pain, even when there’s no injury, and it hopes to find better ways to help manage their pain.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-10904661 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain's neural mechanisms contribute to heightened sensitivity to pain in individuals with chronic overlapping pain conditions. By examining how the central nervous system processes pain signals, the study aims to uncover the reasons behind increased pain responses even in the absence of harmful stimuli. Patients will undergo quantitative sensory testing and advanced computational methods to assess their sensory processing and brain connectivity. The findings could lead to better understanding and treatment options for those suffering from chronic pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic overlapping pain conditions, such as fibromyalgia or other chronic pain syndromes.
Not a fit: Patients with acute pain conditions or those not experiencing chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic pain conditions, enhancing the quality of life for patients.
How similar studies have performed: Previous research has shown promising results in understanding pain mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LARKIN, TONY EDWARD — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: LARKIN, TONY EDWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: CNS Diseases, CNS disorder, Central Nervous System Diseases, Central Nervous System Disorders