Understanding how the brain processes fear and decision-making

A Long-range Recurrent Neural Network Mediates Threat Induced Innate Sensorimotor Integrations

NIH-funded research University of Wyoming · NIH-10626968

This study is looking at how different parts of the brain work together to help us respond to scary situations, which could lead to better ways to treat anxiety and fear-related issues.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Wyoming NIH-funded
Lab location1 site (Laramie, United States)
Project IDNIH-10626968 on NIH RePORTER

What this research studies

This research investigates how the brain integrates sensory information to respond to threats, focusing on a specific neural network that connects emotional regions with motor control areas. By studying the interactions between the amygdala, frontal cortex, and other brain regions, the research aims to uncover the mechanisms behind fear-related behaviors. The approach involves examining how these neural circuits function in response to aversive stimuli, which could provide insights into anxiety and other mental health disorders. The findings may help in developing new strategies for treating conditions related to fear and anxiety.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing anxiety disorders or other mental health issues related to fear responses.

Not a fit: Patients with non-psychological conditions or those not experiencing anxiety or fear-related disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for anxiety and other mental health disorders by enhancing our understanding of the brain's response to fear.

How similar studies have performed: Other research has shown success in understanding neural mechanisms of fear and anxiety, suggesting that this approach could yield valuable insights.

Where this research is happening

Laramie, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.