Understanding how the brain predicts visual information using ferrets
Flexible normalization in ferret V1: computational modeling and 2-photon imaging
['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-10880689
This study looks at how the brain uses what it has learned from past experiences to understand what we see, using ferrets to explore how different brain cells respond during visual tasks, which could help us learn more about how we perceive things and improve treatments for cognitive disorders.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10880689 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain uses past experiences to predict visual stimuli, focusing on the mechanisms of flexible normalization in the visual cortex. By employing advanced 2-photon imaging techniques in ferrets, the study aims to quantify the responses of different types of neurons during various visual tasks. The ferret model is chosen due to its unique neural organization, which allows for a better understanding of how visual information is processed compared to other models. The findings could provide insights into the neural basis of perception and inform future therapies for cognitive disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with cognitive disorders or visual processing issues.
Not a fit: Patients with conditions unrelated to visual processing or cognitive function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of visual processing and lead to improved treatments for cognitive disorders.
How similar studies have performed: While the specific approach of using ferrets for this type of imaging is relatively novel, similar studies in other models have shown promising results in understanding neural mechanisms.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SMITH, GORDON BRAWN — UNIVERSITY OF MINNESOTA
- Study coordinator: SMITH, GORDON BRAWN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bipolar Disorder