Understanding how the brain encodes memories in sequences
Official title: Generation Mechanisms of Memory-Related Internal Sequences in the Hoppocampal CA1 Region
Funded at Max Planck Florida Corporation · NIH-11082495 · Data updated 2026-11-12
This study is looking at how our brains create and store memories, especially focusing on a part of the brain called the hippocampus, and it’s designed for anyone interested in understanding how memories work, including those with memory issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Max Planck Florida Corporation NIH-funded |
| Lab location | 1 site (Jupiter, UNITED STATES) |
| Project start | May 15, 2021 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $482,500 |
| NIH project number | 5R01NS119503-05 |
| Project ID | NIH-11082495 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing early symptoms of memory impairment or those diagnosed with Alzheimer's disease.
✕Less likely to help
Patients with non-memory-related cognitive disorders or those without any cognitive impairment may not benefit from this research.
What this research studies
This research investigates the mechanisms by which the brain segments experiences into distinct memories, focusing on the hippocampus, a critical area for memory formation. By using advanced techniques to manipulate sensory inputs, the study aims to differentiate between memory-related neural activity and that driven by external stimuli. This approach allows researchers to explore how internal sequences of activity contribute to the encoding of episodic memories. The findings could provide insights into memory processes in both healthy individuals and those with memory-related disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for memory-related conditions such as Alzheimer's disease.
How similar studies have gone: Previous research has shown promising results in understanding memory encoding through similar neural circuit approaches, indicating potential for significant advancements in this area.
Where this research is happening
-
Max Planck Florida Corporation
Jupiter, United States Active
Researchers
- Principal investigator: Wang, Yingxue — Max Planck Florida Corporation
- Study coordinator: Wang, Yingxue
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.