Understanding how brain signaling affects learning and memory.
Neuronal Intracellular Signaling Underlying Synaptic, Circuit and Behavioral Plasticity
['FUNDING_OTHER'] · MAX PLANCK FLORIDA CORPORATION · NIH-11091597
This study is looking at how tiny parts of brain cells help us learn and remember, using special tools to see and change their activity in both brain samples and living animals, so we can better understand how our brains work.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAX PLANCK FLORIDA CORPORATION (nih funded) |
| Locations | 1 site (Jupiter, UNITED STATES) |
| Trial ID | NIH-11091597 on ClinicalTrials.gov |
What this research studies
This research investigates the intricate signaling processes within dendritic spines of neurons, which are crucial for learning and memory. By utilizing advanced imaging techniques and optogenetic tools, the study aims to measure and manipulate these signaling activities in both brain slices and live animals. The goal is to uncover how these signaling pathways contribute to synaptic and behavioral plasticity, ultimately enhancing our understanding of brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with non-neurological conditions or those without cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cognitive function in patients with Alzheimer's disease and other forms of dementia.
How similar studies have performed: Previous research has shown promising results in understanding neuronal signaling and its implications for cognitive function, suggesting that this approach could yield significant insights.
Where this research is happening
Jupiter, UNITED STATES
- MAX PLANCK FLORIDA CORPORATION — Jupiter, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YASUDA, RYOHEI — MAX PLANCK FLORIDA CORPORATION
- Study coordinator: YASUDA, RYOHEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease