Understanding how the brain compensates after a stroke

ERIS - Effective Reserve In Stroke

NIH-funded research Massachusetts General Hospital · NIH-10724761

This study is looking at how the brain can adapt after a stroke to help people recover better, especially older adults, so we can find new ways to support their healing and independence.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10724761 on NIH RePORTER

What this research studies

This research investigates how the brain's ability to compensate for damage caused by a stroke can influence recovery and functional independence. By analyzing clinical imaging data from patients with acute ischemic stroke, the study aims to identify factors that contribute to better-than-expected outcomes. The goal is to develop targeted treatment options that enhance recovery by understanding the brain's effective reserve capacity. This approach is particularly relevant for older adults who are at higher risk for strokes and related disabilities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced an acute ischemic stroke, particularly older adults.

Not a fit: Patients who have not had a stroke or those with other unrelated neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery strategies for stroke patients, enhancing their quality of life and independence.

How similar studies have performed: Previous research has shown promise in understanding brain reserve in neurodegenerative diseases, but this specific approach in stroke populations is relatively novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cerebrovascular DisordersBrain Vascular DisordersCerebrovascular DiseaseIntracranial Vascular DiseasesIntracranial Vascular Disorders
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.