Understanding how the body responds to stress from infections
Response to Immune Associated Stress
This study is looking at how our bodies handle stress during infections by focusing on certain proteins, and it hopes to find new ways to help people with autoimmune and infectious diseases feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10823388 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which the body manages stress during infections, focusing on specific proteins that play a role in this response. The study aims to identify new factors that regulate a key transcription factor, SKN-1, which is crucial for protecting the body from immune-related stress. By exploring how these proteins interact and influence each other, the research seeks to uncover potential therapeutic targets that could help alleviate the negative effects of infections. Patients may benefit from insights gained that could lead to new treatments for autoimmune and infectious diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from autoimmune diseases or those with recurrent infections.
Not a fit: Patients with non-infectious conditions or those not affected by autoimmune disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve the body's ability to cope with infections and reduce the severity of autoimmune conditions.
How similar studies have performed: Previous research has shown promise in understanding immune responses and stress management, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Garsin, Danielle a — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Garsin, Danielle a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.