Understanding how the anterior cingulate cortex affects cognitive control in the brain
Investigation of Anterior Cingulate Cortex Contributions to Hippocampal Cognitive Control
This study is looking at how a part of the brain called the anterior cingulate cortex helps with decision-making and staying focused, using rats to see how this area works when they navigate tasks, and it will also check what happens when this part of the brain is temporarily turned off.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10933450 on NIH RePORTER |
What this research studies
This research investigates the role of the anterior cingulate cortex (ACC) in cognitive control, which is essential for making decisions and monitoring performance. Using advanced techniques like in-vivo single photon calcium imaging, the study will observe neuron activity in the ACC while rats engage in tasks that require navigation and cognitive control. Additionally, the research will employ chemogenetic methods to temporarily deactivate the ACC to assess its necessity during these tasks. The findings aim to clarify how the ACC contributes to cognitive control alongside the hippocampus.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with cognitive control challenges, such as those with neurological disorders affecting decision-making.
Not a fit: Patients with conditions unrelated to cognitive control or those who do not exhibit cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cognitive control mechanisms, potentially leading to improved treatments for cognitive impairments.
How similar studies have performed: Previous research has shown promising results in understanding cognitive control through similar methodologies, indicating a potential for success in this investigation.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Blair, Garrett — New York University
- Study coordinator: Blair, Garrett
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.