Understanding how T cells respond to infections and tumors
Regulatory genomics of T cells in mouse and human
['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-10863921
This study is looking at how T cells, which are important for fighting infections and cancer, work and change in response to different signals, using both mouse and human samples to help improve future treatments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-10863921 on ClinicalTrials.gov |
What this research studies
This research investigates the activation and differentiation of T cells, which are crucial for the immune response against infections and tumors. By using advanced genomics techniques, the team aims to create detailed data resources and develop computational methods to analyze how T cells respond to various stimuli. The study will explore the regulatory mechanisms that guide T cell behavior, comparing findings from mouse models to human responses. This comprehensive approach will enhance our understanding of T cell function and could inform future therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with autoimmune conditions, infections, or cancers that involve T cell responses.
Not a fit: Patients with conditions unrelated to T cell function or those who do not have an active immune response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for infections and cancers by enhancing our understanding of T cell behavior.
How similar studies have performed: Other research has shown success in using genomics to understand immune responses, indicating that this approach has potential for significant findings.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRITYKIN, YURY — PRINCETON UNIVERSITY
- Study coordinator: PRITYKIN, YURY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections