Understanding how sugar molecules affect animal development and diseases.
Roles of Glycosylation and Deglycosylation During Animal Development
This study is looking at how adding sugar molecules to proteins affects animal growth and health, especially in understanding certain birth disorders, with the hope of finding new ways to treat diseases linked to this process.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11136318 on NIH RePORTER |
What this research studies
This research investigates the role of glycosylation, the process of adding sugar molecules to proteins, in animal development and various diseases. By studying how these sugar modifications influence protein function and signaling pathways, the research aims to uncover the underlying mechanisms of congenital disorders related to glycosylation. The approach includes analyzing the effects of glycosylation on cell communication and the development of specific tissues. Ultimately, the goal is to provide insights that could lead to new therapeutic strategies for treating glycosylation-related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with congenital disorders of glycosylation or related conditions, particularly those under 21 years old.
Not a fit: Patients with conditions unrelated to glycosylation or those over 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for congenital disorders of glycosylation, improving health outcomes for affected individuals.
How similar studies have performed: Previous research has shown promising results in understanding glycosylation's role in cell signaling, indicating potential for success in this area.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Jafar-Nejad, Hamed — Baylor College of Medicine
- Study coordinator: Jafar-Nejad, Hamed
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.