Understanding how stress and rewards influence substance use in young women

Reward Enhancement and Stress as Cues for Substance use (RESCUES)

NIH-funded research University of Nebraska Lincoln · NIH-11052496

This study is looking at how stress and certain rewards can lead to substance use in young women, especially those who are bisexual, to find better ways to help prevent substance use problems and support their unique experiences.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Lincoln NIH-funded
Lab location1 site (Lincoln, United States)
Project IDNIH-11052496 on NIH RePORTER

What this research studies

This research investigates the unique factors that contribute to substance use among young women, particularly focusing on how stress and cues related to rewards can trigger cravings. It aims to identify effective intervention points to prevent substance use disorders by considering the specific experiences of women, especially those who are bisexual. The study will analyze the interplay between mood disorders, anxiety, and substance use, aiming to disrupt harmful patterns through targeted interventions. By understanding these dynamics, the research seeks to develop tailored strategies for treatment and prevention.

Who could benefit from this research

Good fit: Ideal candidates for this research are young women, particularly those who experience stress-related cravings or have a history of substance use.

Not a fit: Patients who are not young women or those without substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for substance use disorders in young women.

How similar studies have performed: Previous research has shown that understanding gender-specific factors in substance use can lead to successful interventions, suggesting this approach has potential.

Where this research is happening

Lincoln, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective DisordersAnxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.