Understanding how stem cells develop into different types of tissues
Official title: Physicochemical control of multilineage emergence
Funded at University of California-Irvine · NIH-10896229 · Data updated 2026-11-12
This study is looking at special cells that can turn into different types of cells in the body to help us learn more about how we grow and how diseases work, with the hope of creating better ways to make tissues for healing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $368,649 |
| NIH project number | 5R35GM151099-02 |
| Project ID | NIH-10896229 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that could benefit from regenerative medicine, such as metabolic diseases or tissue damage.
✕Less likely to help
Patients with conditions that do not involve tissue regeneration or metabolic disorders may not benefit from this research.
What this research studies
This research investigates the behavior of human induced pluripotent stem cells (iPSCs), which can transform into various cell types. By examining how these cells interact with their environment and each other, the study aims to improve our understanding of human development and disease. The researchers will use advanced techniques like micropatterned models and microfluidics to create more accurate tissue models. This approach could lead to better methods for generating tissues for regenerative medicine.
Why it matters
Potential benefit: If successful, this research could enhance the development of patient-specific tissues for regenerative therapies.
How similar studies have gone: Previous research has shown promise in using iPSCs for tissue engineering, indicating that this approach could lead to significant advancements.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Smith, Quinton — University of California-Irvine
- Study coordinator: Smith, Quinton
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.