Understanding how snails and schistosomes interact to improve treatment for schistosomiasis
Genetic mechanisms of snail/schistosome compatibility
This study is looking at how some snails can fight off the parasites that cause schistosomiasis, with the hope of finding new ways to help control the disease by understanding the genes that make these snails resistant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project ID | NIH-11084454 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms that allow certain snails to resist infection by schistosomes, the parasites responsible for schistosomiasis. By studying the interactions between these snails and the parasites, researchers aim to identify specific genes that contribute to this resistance. The approach involves analyzing the genetic makeup of a resistant strain of snails to uncover potential targets for new treatment strategies. This could lead to innovative methods for controlling schistosomiasis transmission by disrupting the life cycle of the parasites at the snail stage.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in regions where schistosomiasis is endemic and who may be at risk of infection.
Not a fit: Patients who are not at risk for schistosomiasis or who live in areas where the disease is not present may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for controlling schistosomiasis, potentially reducing the disease's prevalence and improving patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding the interactions between snails and schistosomes, but this specific genetic approach is relatively novel.
Where this research is happening
Corvallis, United States
- Oregon State University — Corvallis, United States (Active)
Researchers
- Principal investigator: Blouin, Michael Scott — Oregon State University
- Study coordinator: Blouin, Michael Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.