Understanding how skin cell communication affects skin health and disease
KLF-mediated coordination of signaling and epigenetic mechanisms in the skin
This study is looking at how certain signals and changes in skin cells affect skin health, with the goal of finding new ways to treat skin problems like skin cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10764790 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between cell signaling and epigenetic mechanisms in the skin, which are crucial for maintaining skin health. By studying how these processes influence gene expression, the research aims to uncover new therapeutic approaches for skin conditions, including various types of skin cancer. The project focuses on specific transcription factors that play a key role in regulating skin cell behavior and gene activity, potentially leading to innovative treatments for skin dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with skin cancers or other skin-related conditions that may benefit from new treatment strategies.
Not a fit: Patients with non-skin-related health issues or those not affected by skin conditions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel therapies for skin cancers and other skin disorders.
How similar studies have performed: Previous research has shown promise in understanding the role of transcription factors in skin health, indicating that this approach could yield significant insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Millar, Sarah E. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Millar, Sarah E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.