Understanding how skin and nerves sense touch and respond to stress
The biophysics of skin-neuron sensory tactile organs and their sensitivity to mechanical and chemical stress
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10995299
This work explores how our skin and nerves work together to sense touch and movement, which is crucial for everyday activities and overall health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10995299 on ClinicalTrials.gov |
What this research studies
Our skin, muscles, and organs contain special nerve cells that help us feel touch and movement, which are vital for daily life. This project aims to understand how mechanical forces on the skin are turned into electrical signals by these nerves, allowing us to perceive touch. Researchers are using advanced tools and combining biology, engineering, and physics to study these processes. They also want to learn how nerves can bend without breaking, which is important for their function.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit individuals with conditions affecting touch and sensation, including those with autoimmune diseases.
Not a fit: Patients seeking immediate clinical interventions or direct treatment options would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of sensory issues in conditions like autoimmune diseases, potentially guiding future treatments for problems with touch and movement.
How similar studies have performed: While the specific combination of techniques and focus on nerve bending is novel, other basic science studies have successfully used model organisms to understand fundamental biological processes relevant to human health.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOODMAN, MIRIAM B — STANFORD UNIVERSITY
- Study coordinator: GOODMAN, MIRIAM B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases