Understanding how signaling lipids affect development and immune responses
Official title: Molecular genetics of signaling lipids
Funded at University of California Riverside · NIH-11058443 · Data updated 2026-11-12
This study is looking at how certain fats in the body, like ecdysone and juvenile hormones, help control important processes in animals, especially fruit flies, to better understand their role in growth and immune health, which could also help us learn more about human health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | April 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $346,433 |
| NIH project number | 5R35GM153331-02 |
| Project ID | NIH-11058443 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in the biological mechanisms of development and immune responses, particularly those with conditions influenced by lipid signaling.
✕Less likely to help
Patients with conditions unrelated to lipid signaling or those not interested in the biological mechanisms of development may not benefit from this research.
What this research studies
This research investigates the role of signaling lipids, such as ecdysone and juvenile hormones, in regulating important physiological processes in animals, particularly focusing on fruit flies. By utilizing advanced genetic techniques, the study aims to uncover how these lipids are transported into cells and how they influence development and immune responses. The research will fill critical knowledge gaps regarding the mechanisms of lipid signaling, which could have implications for human health and development.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how lipid signaling affects human health, potentially informing treatments for developmental and immune-related conditions.
How similar studies have gone: While the study of signaling lipids is a growing field, this specific approach utilizing fruit fly genetics to explore lipid transport mechanisms is relatively novel and has not been extensively tested.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Yamanaka, Naoki — University of California Riverside
- Study coordinator: Yamanaka, Naoki
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.