Understanding how serotonin affects brain function and behavior
Deconstructing the sertonin system in the mouse brain
This study is looking at how different types of serotonin neurons in the mouse brain work and connect with other brain areas to help us understand their role in behaviors and conditions like anxiety and depression.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10656870 on NIH RePORTER |
What this research studies
This research investigates the organization and function of serotonin neurons in the mouse brain, focusing on how these neurons influence various behaviors and physiological processes. By examining the distinct types of serotonin neurons and their specific connections to different brain regions, the study aims to uncover the complex roles serotonin plays in conditions like anxiety and depression. The approach includes advanced techniques such as single-cell transcriptomic profiling and collateralization mapping to provide a detailed understanding of serotonin's impact on brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety, depression, or related mental health disorders.
Not a fit: Patients with conditions unrelated to serotonin dysfunction or those not experiencing mental health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for anxiety, depression, and other brain disorders by enhancing our understanding of the serotonin system.
How similar studies have performed: Previous research has shown promising results in understanding the serotonin system, indicating that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Luo, Liqun — Stanford University
- Study coordinator: Luo, Liqun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.