Understanding how reproductive organs develop in embryos
Official title: Reproductive tract organ development and differentiation
Funded at University of Tx Md Anderson Can Ctr · NIH-11141909 · Data updated 2026-11-12
This study looks at how male and female reproductive organs form in baby mammals and how hormones influence this process, aiming to better understand conditions that can affect sexual development and fertility.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 19, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $487,400 |
| NIH project number | 5R01HD113569-02 |
| Project ID | NIH-11141909 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with Differences of Sex Development (DSD) or those experiencing reproductive health issues related to organ development.
✕Less likely to help
Patients without any reproductive tract disorders or those not experiencing difficulties related to sexual development may not benefit from this research.
What this research studies
This research investigates the development of male and female reproductive organs in mammalian embryos, focusing on the role of fetal gonadal hormones in determining sex differentiation. It examines the formation of paired epithelial ducts in the fetal kidneys, which develop into male or female reproductive structures depending on hormonal influences. By studying the mechanisms behind these processes, the research aims to uncover the causes of Differences of Sex Development (DSD) and related reproductive disorders, which can affect fertility and organ formation.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals with reproductive tract disorders and difficulties conceiving.
How similar studies have gone: Previous research has shown promising results in understanding reproductive organ development, making this a continuation of established scientific inquiry.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Behringer, Richard R — University of Tx Md Anderson Can Ctr
- Study coordinator: Behringer, Richard R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.