Understanding how preventive medicines work for older adults

Propensity scores and preventive drug use in the elderly

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11125915

This project helps us learn more accurately about how well preventive medicines and treatments work for older adults, especially those with many health conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11125915 on NIH RePORTER

What this research studies

Many older adults, especially those with several health issues, are not often included in traditional clinical trials that test new treatments. This means we often need to look at real-world health information to understand how well medicines, surgeries, and vaccines work for them. However, it can be challenging to get accurate answers from this real-world data because many other factors, like overall health or frailty, can also affect outcomes. This project focuses on developing and improving special methods to carefully analyze this real-world information. Our goal is to ensure that treatment decisions for older adults are based on the most reliable and accurate evidence available.

Who could benefit from this research

Good fit: This research focuses on improving health outcomes for older adults, particularly those living with multiple chronic conditions and taking several medications.

Not a fit: Patients seeking direct medical treatment or immediate health interventions would not directly benefit from this methodological research.

Why it matters

Potential benefit: If successful, this work will provide more reliable information about the benefits and risks of preventive treatments, helping older adults and their doctors make informed health decisions.

How similar studies have performed: The researchers have a long history of successful work in this area, with previous grants contributing to significant advancements in these analytical methods.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Chronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.