Understanding how pneumonia affects recovery after spinal cord injury
Protecting endogenous recovery from the "infectious insult" in Spinal Cord Injury
['FUNDING_R01'] · OHIO STATE UNIVERSITY · NIH-10981536
This study is looking at how pneumonia affects recovery after a spinal cord injury, using mice to see if the infection makes healing harder and to find ways to help protect the nervous system during recovery.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-10981536 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of pneumonia on recovery following spinal cord injury (SCI). By using a mouse model, the study aims to determine if pneumonia directly worsens neurological recovery by analyzing the interactions between the immune response and the injured spinal cord. The researchers will explore how bacterial infections influence the healing process and identify potential neuroprotective interventions. This work employs advanced techniques to visualize and understand the underlying mechanisms of injury and repair.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a spinal cord injury and are at risk of developing pneumonia.
Not a fit: Patients who have not experienced a spinal cord injury or those without a risk of pneumonia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery strategies for patients with spinal cord injuries who develop pneumonia.
How similar studies have performed: Previous research has shown that infections can significantly impact recovery in various conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHWAB, JAN — OHIO STATE UNIVERSITY
- Study coordinator: SCHWAB, JAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bacterial Infections