NIH-funded research R21 grant

Understanding how people navigate spaces and its link to mental health

Official title: Characterizing the cognitive computations underlying spatial navigation

Funded at University of Arizona · NIH-10726662 · Data updated 2026-11-12

This study is looking at how problems with finding your way around might connect to mental health issues like anxiety, depression, and schizophrenia, and it aims to create new ways to understand and test these navigation challenges in a friendly and helpful way.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startSeptember 5, 2023
Project endSeptember 4, 2025
Funding year2023
Award (this year)$411,919
NIH project number1R21MH134100-01
Project IDNIH-10726662 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with anxiety, depression, autism, or schizophrenia who experience difficulties with spatial navigation.

Less likely to help

Patients without any mental health disorders or those who do not experience navigation difficulties may not benefit from this research.

What this research studies

This research investigates how deficits in spatial navigation relate to various mental disorders such as anxiety, depression, and schizophrenia. It aims to develop new computational models and behavioral tests that better capture the cognitive processes involved in navigating spaces. By using innovative methods that incorporate body movement and environmental cues, the study seeks to uncover the underlying neural mechanisms that contribute to navigation difficulties in affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for mental health disorders associated with navigation deficits.

How similar studies have gone: Previous research has shown promise in understanding navigation deficits in mental health, but this approach aims to provide novel insights through advanced computational modeling.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Ekstrom, Arne D — University of Arizona
  • Study coordinator: Ekstrom, Arne D

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.