Understanding how nuclear shape is regulated in cells
Mechanisms of nuclear morphology regulation
This study is looking at how the size and shape of cell nuclei can change in cancer, using tiny worms and human stem cells to find out how these changes might help us understand and treat cancer better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wyoming NIH-funded |
| Lab location | 1 site (Laramie, United States) |
| Project ID | NIH-11074098 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that control the size and shape of the nucleus in cells, particularly in the context of cancer. By using various experimental approaches, including studies in model organisms like C. elegans and human stem cells, the research aims to uncover how changes in nuclear morphology can affect cancer diagnosis and progression. The team will explore both normal and stress conditions to understand the underlying biological processes. This work could lead to new insights into cancer biology and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancer or those at risk of developing cancer, particularly those interested in the biological mechanisms of their condition.
Not a fit: Patients with non-cancerous conditions or those not interested in the biological aspects of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve cancer diagnosis and treatment by providing new insights into the role of nuclear morphology in cancer progression.
How similar studies have performed: While the specific focus on nuclear morphology in cancer is a novel approach, related studies have shown success in understanding cellular mechanisms in cancer biology.
Where this research is happening
Laramie, United States
- University of Wyoming — Laramie, United States (Active)
Researchers
- Principal investigator: Levy, Daniel Leon — University of Wyoming
- Study coordinator: Levy, Daniel Leon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.