Understanding how Neuropeptide S affects sleep and anxiety
Neuropeptide S and arousal
This work explores how a brain chemical called Neuropeptide S influences our sleep patterns and feelings of anxiety.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11135379 on NIH RePORTER |
What this research studies
Researchers are looking into a brain chemical called Neuropeptide S, which plays a key role in how we sleep and stay awake. They want to understand how this chemical works in the brain to control sleep and anxiety. By studying specific brain cells that produce Neuropeptide S, they aim to map out their connections and observe their activity during different sleep stages, stress, and positive emotions. This will help us learn more about the brain's natural systems for regulating these important functions.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future studies building on this work may seek individuals with sleep or anxiety disorders.
Not a fit: Patients not experiencing sleep disturbances or anxiety disorders would likely not directly benefit from this specific line of research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to help people with sleep disorders and anxiety by targeting the Neuropeptide S system.
How similar studies have performed: Previous findings suggest Neuropeptide S influences wakefulness and anxiety, and mutations in its receptor are linked to short sleep in humans, indicating this is a promising area of investigation.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: De Lecea, Luis — Stanford University
- Study coordinator: De Lecea, Luis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.