Understanding how neurons and astrocytes communicate in the brain
S1P-S1PR1 in bidirectional Neuron-Astrocyte communications
This study looks at how brain cells called neurons and support cells called astrocytes work together to keep our brains healthy, and it hopes to find out how problems in their communication might lead to brain disorders, which could help patients understand their conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-11178293 on NIH RePORTER |
What this research studies
This research investigates the interactions between neurons and astrocytes, which are crucial for brain development and function. It focuses on how neuronal signals influence the growth and maturation of astrocytes, while astrocytes provide essential support for neurons. By exploring the molecular mechanisms behind these interactions, the research aims to uncover how these processes affect brain health and disease. Patients may benefit from insights into how disruptions in these communications could lead to brain disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions that may involve disrupted neuron-astrocyte communication.
Not a fit: Patients with purely peripheral nervous system disorders or those without any neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for brain disorders by targeting the communication pathways between neurons and astrocytes.
How similar studies have performed: Previous research has shown promising results in understanding neuron-astrocyte interactions, indicating that this approach has potential for significant findings.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Singh, Sandeep Kumar — Virginia Commonwealth University
- Study coordinator: Singh, Sandeep Kumar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.