Understanding how neural circuits form and influence behavior

Developmental and Genetic Basis of Neural Circuit Formation and Behavior

NIH-funded research University of Missouri Kansas City · NIH-11137787

This study is looking at how certain genes and brain cells in fruit flies help create the connections in their nervous system that control behaviors like walking and grooming, which could help us understand how our own brains work.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Missouri Kansas City NIH-funded
Lab location1 site (Kansas City, United States)
Project IDNIH-11137787 on NIH RePORTER

What this research studies

This research investigates the genetic and cellular mechanisms that drive the formation of neural circuits and their impact on behavior using the Drosophila (fruit fly) model. By examining the adult ventral nerve cord, which is responsible for various behaviors such as walking and grooming, the study aims to identify the specific genes and neural pathways involved in these processes. The research employs advanced genetic techniques to dissect the roles of different neuron types and their connectivity patterns. This approach could provide insights into the fundamental principles of nervous system development and function.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with genetic or developmental disorders affecting neural function.

Not a fit: Patients with purely psychological conditions unrelated to neural circuit formation may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of neural circuit formation, potentially leading to new treatments for neurological disorders.

How similar studies have performed: Other research has shown success in using Drosophila models to uncover genetic mechanisms of neural development, indicating that this approach is promising.

Where this research is happening

Kansas City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.