Understanding how neural circuits form and influence behavior
Official title: Developmental and Genetic Basis of Neural Circuit Formation and Behavior
Funded at University of Missouri Kansas City · NIH-11137787 · Data updated 2026-11-12
This study is looking at how certain genes and brain cells in fruit flies help create the connections in their nervous system that control behaviors like walking and grooming, which could help us understand how our own brains work.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri Kansas City NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $391,250 |
| NIH project number | 5R01NS122903-04 |
| Project ID | NIH-11137787 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with genetic or developmental disorders affecting neural function.
✕Less likely to help
Patients with purely psychological conditions unrelated to neural circuit formation may not receive benefit from this research.
What this research studies
This research investigates the genetic and cellular mechanisms that drive the formation of neural circuits and their impact on behavior using the Drosophila (fruit fly) model. By examining the adult ventral nerve cord, which is responsible for various behaviors such as walking and grooming, the study aims to identify the specific genes and neural pathways involved in these processes. The research employs advanced genetic techniques to dissect the roles of different neuron types and their connectivity patterns. This approach could provide insights into the fundamental principles of nervous system development and function.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of neural circuit formation, potentially leading to new treatments for neurological disorders.
How similar studies have gone: Other research has shown success in using Drosophila models to uncover genetic mechanisms of neural development, indicating that this approach is promising.
Where this research is happening
-
University of Missouri Kansas City
Kansas City, United States Active
Researchers
- Principal investigator: Lacin, Haluk — University of Missouri Kansas City
- Study coordinator: Lacin, Haluk
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.