Understanding how mitochondria change during aging
Investigating spatial and temporal heterogeneity in mitochondria during aging using in vivo high-content chemical imaging
This study looks at how the tiny powerhouses in our cells, called mitochondria, change as we get older, and it’s designed for older adults to help us understand how these changes affect our health as we age.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11145918 on NIH RePORTER |
What this research studies
This research investigates how mitochondria, the energy-producing structures in cells, change in both location and function as people age. Using advanced imaging techniques, the study will observe these changes in real-time within living organisms, specifically focusing on older adults. By examining the relationship between mitochondrial behavior and overall cellular health, the research aims to uncover important insights into aging and related conditions. The findings could help identify potential interventions to improve health in older populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older, particularly those interested in understanding the biological processes of aging.
Not a fit: Patients under the age of 65 or those without age-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing cellular health and potentially delaying age-related diseases in older adults.
How similar studies have performed: Previous research has shown promising results in understanding mitochondrial function and aging, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Chen, Wei-Wen — Georgia Institute of Technology
- Study coordinator: Chen, Wei-Wen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.