Understanding how mental health affects COVID-19 risks and outcomes
Leveraging genomic data to dissect the association of internalizing disorders with the risk, onset, and vulnerability of COVID-19
This study is looking at how anxiety and depression might affect your risk of getting COVID-19 and how seriously it could impact you, and it’s for anyone who has these mental health conditions and wants to help us understand this connection better by sharing some health information and genetic samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10612299 on NIH RePORTER |
What this research studies
This research investigates the relationship between internalizing disorders, such as anxiety and depression, and the risk and severity of COVID-19. By analyzing genomic data, the study aims to uncover how mental health conditions may influence susceptibility to the virus and its severe effects. The approach involves a network analysis to connect various health domains impacted by COVID-19, focusing on the psychological stress and trauma experienced during the pandemic. Patients may be asked to provide genetic samples and health information to help identify these associations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of internalizing disorders, such as anxiety or depression, particularly those affected during the COVID-19 pandemic.
Not a fit: Patients without any mental health disorders or those who have not been impacted by COVID-19 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved mental health interventions that reduce the risk and severity of COVID-19 in vulnerable populations.
How similar studies have performed: Previous research has indicated a link between mental health and infectious disease outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Polimanti, Renato — Yale University
- Study coordinator: Polimanti, Renato
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.