Understanding how memories are stored and retrieved in the brain
Single-cell and target-specific resolution of multiple memories across the brain
This study is exploring how our brains store different memories and how they work together, which could help us understand memory problems like Alzheimer's disease better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10689742 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind how multiple memories are stored across different regions of the brain. By using advanced imaging techniques and behavioral assays, the study aims to create a detailed map of memory traces and their dynamics in real-time. The approach involves tagging neurons that are active during memory formation and retrieval, allowing researchers to analyze how these memories interact and influence behavior. This could lead to a better understanding of memory-related disorders, particularly in conditions like Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias who are experiencing memory issues.
Not a fit: Patients with memory disorders not related to Alzheimer's or those with other neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for patients suffering from memory-related disorders such as Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in understanding memory mechanisms, but this approach aims to provide novel insights that have not been extensively tested.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Denny, Christine Ann — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Denny, Christine Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.