Understanding how lung stem cells behave in health and disease
Official title: Regulation of Progenitor Cell Plasticity in Lung Development and Disease-Repair
Funded at Columbia University Health Sciences · NIH-10872135 · Data updated 2026-11-12
This study is looking at how lung stem cells work and change when we have diseases like COPD, with the hope that what we learn can help create better treatments for people with lung problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2030 |
| Funding year | 2024 |
| Award (this year) | $1,095,516 |
| NIH project number | 5R35HL166661-02 |
| Project ID | NIH-10872135 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic lung diseases, particularly those affected by COPD.
✕Less likely to help
Patients with acute lung conditions or those without chronic lung diseases may not receive direct benefits from this research.
What this research studies
This research investigates the behavior of lung stem cells during development and in response to diseases like COPD. It aims to understand how these cells can change states between normal function and abnormal repair processes. By studying both human and animal models, the research will explore the origins of lung cell behavior and its implications for chronic lung diseases. Patients may benefit from insights that could lead to new treatments for lung conditions.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies for chronic lung diseases, improving patient outcomes.
How similar studies have gone: Other research has shown promise in understanding lung cell behavior, but this approach is exploring new territory in the context of lung development and chronic disease.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Cardoso, Wellington V. — Columbia University Health Sciences
- Study coordinator: Cardoso, Wellington V.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.