Understanding how lung memory T cells protect against COVID-19
The generation and protective function of lung tissue resident memory T cells following SARS-CoV-2 infection or vaccination
This study is looking at how certain immune cells in the lungs help protect us from COVID-19 and its variants after we've been infected or vaccinated, and it aims to find ways to make vaccines even better, so your participation could really help us understand this important part of our immune system!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11042145 on NIH RePORTER |
What this research studies
This research investigates the role of lung tissue resident memory T cells in providing long-lasting immunity against SARS-CoV-2 infection and its variants. By examining the immune responses generated after COVID-19 infection or vaccination, the study aims to determine how these memory T cells contribute to protection in the lungs. The approach includes analyzing the types and longevity of these immune cells, which may offer insights into improving vaccine strategies and enhancing long-term immunity. Patients may be involved in providing samples or data to help understand these immune responses better.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been infected with SARS-CoV-2 or vaccinated against COVID-19.
Not a fit: Patients who have not been infected with SARS-CoV-2 and have not received a COVID-19 vaccine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and therapies that provide better protection against COVID-19 and its variants.
How similar studies have performed: Previous research on memory T cells in response to other coronaviruses has shown promising results, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- Scripps Research Institute, the — La Jolla, United States (Active)
Researchers
- Principal investigator: Teijaro, John Ross — Scripps Research Institute, the
- Study coordinator: Teijaro, John Ross
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.