Understanding how kidneys heal after injury
Official title: Glomerular and Tubular Function in the Recovering Kidney
Funded at Veterans Medical Research Fdn/san Diego · NIH-10978209 · Data updated 2026-11-12
This study looks at how kidneys heal after an injury by using rats to see the tiny changes that happen during recovery, with the hope of finding better ways to help people fully recover from kidney damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Medical Research Fdn/san Diego NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | January 1, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $393,810 |
| NIH project number | 5R01DK132690-03 |
| Project ID | NIH-10978209 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced acute kidney injury and are in the recovery phase.
✕Less likely to help
Patients with chronic kidney disease or those who have not experienced acute kidney injury may not benefit from this research.
What this research studies
This research investigates the recovery process of kidneys following acute injury, focusing on how they function and adapt during healing. By using rat models, the study aims to uncover the microscopic changes that occur in the kidneys, which are not observable in humans. The goal is to identify the reasons behind incomplete recovery and the potential for targeted interventions that could improve healing and prevent long-term damage. This research addresses critical knowledge gaps that currently hinder effective treatment strategies for patients recovering from kidney injuries.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that enhance kidney recovery and reduce the risk of long-term complications for patients with acute kidney injury.
How similar studies have gone: While the approach of using rat models to study kidney recovery is established, the specific focus on the microscopic mechanisms of recovery in this context is relatively novel.
Where this research is happening
-
Veterans Medical Research Fdn/san Diego
San Diego, United States Active
Researchers
- Principal investigator: Thomson, Scott Culver — Veterans Medical Research Fdn/san Diego
- Study coordinator: Thomson, Scott Culver
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.