Understanding how kidneys heal after injury
Glomerular and Tubular Function in the Recovering Kidney
This study looks at how kidneys heal after an injury by using rats to see the tiny changes that happen during recovery, with the hope of finding better ways to help people fully recover from kidney damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Medical Research Fdn/san Diego NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-10978209 on NIH RePORTER |
What this research studies
This research investigates the recovery process of kidneys following acute injury, focusing on how they function and adapt during healing. By using rat models, the study aims to uncover the microscopic changes that occur in the kidneys, which are not observable in humans. The goal is to identify the reasons behind incomplete recovery and the potential for targeted interventions that could improve healing and prevent long-term damage. This research addresses critical knowledge gaps that currently hinder effective treatment strategies for patients recovering from kidney injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced acute kidney injury and are in the recovery phase.
Not a fit: Patients with chronic kidney disease or those who have not experienced acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that enhance kidney recovery and reduce the risk of long-term complications for patients with acute kidney injury.
How similar studies have performed: While the approach of using rat models to study kidney recovery is established, the specific focus on the microscopic mechanisms of recovery in this context is relatively novel.
Where this research is happening
San Diego, United States
- Veterans Medical Research Fdn/san Diego — San Diego, United States (Active)
Researchers
- Principal investigator: Thomson, Scott Culver — Veterans Medical Research Fdn/san Diego
- Study coordinator: Thomson, Scott Culver
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.