Understanding how kidney issues affect the brain in children with severe malaria
Delineating the kidney brain axis in children with severe malaria (KID-BRAIN)
This study is looking at how kidney problems can affect the brain in young children with severe malaria, and it aims to find ways to help improve their health and recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Makerere University College of Health Sciences NIH-funded |
| Lab location | 1 site (Kampala, Uganda) |
| Project ID | NIH-11078759 on NIH RePORTER |
What this research studies
This research investigates the connection between kidney injury and brain damage in children suffering from severe malaria. The principal investigator, Dr. Batte, aims to identify the mechanisms that lead to brain injury due to kidney problems, focusing on children under 11 years old. The study will utilize advanced diagnostic techniques and follow-up assessments to evaluate the long-term effects of acute kidney injury on brain health. By understanding these relationships, the research seeks to develop interventions that can improve outcomes for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old who are experiencing acute kidney injury due to severe malaria.
Not a fit: Patients who do not have acute kidney injury or are not suffering from severe malaria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and better long-term health outcomes for children with acute kidney injury related to severe malaria.
How similar studies have performed: Previous research has shown promising results in understanding kidney-brain interactions in other contexts, but this specific focus on severe malaria in children is relatively novel.
Where this research is happening
Kampala, Uganda
- Makerere University College of Health Sciences — Kampala, Uganda (Active)
Researchers
- Principal investigator: Batte, Anthony — Makerere University College of Health Sciences
- Study coordinator: Batte, Anthony
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.