Understanding how iron imbalance affects kidney fibrosis and finding ways to protect the kidneys.
Official title: Mechanisms of intracellular iron dysregulation in kidney fibrosis and reno-protective strategies
Funded at Weill Medical Coll of Cornell Univ · NIH-11171292 · Data updated 2026-11-12
This study is looking at how problems with iron in the body might affect kidney health in people with chronic kidney disease, and it aims to find new ways to help protect the kidneys and slow down damage.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 5, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $199,922 |
| NIH project number | 1R56DK136876-01A1 |
| Project ID | NIH-11171292 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic kidney disease, particularly those experiencing complications related to iron dysregulation.
✕Less likely to help
Patients with acute kidney injury or those without chronic kidney disease may not benefit from this research.
What this research studies
This research investigates the role of iron dysregulation in the progression of chronic kidney disease (CKD) and kidney fibrosis. It focuses on how kidney cells respond to iron levels and aims to identify new therapeutic targets to slow down kidney damage. By studying the protective mechanisms of kidney cells, the research seeks to enhance these processes to prevent further complications in CKD patients. The ultimate goal is to develop strategies that could improve kidney health and patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow the progression of chronic kidney disease and improve the quality of life for patients.
How similar studies have gone: Previous research has shown promising results in targeting iron dysregulation in kidney diseases, indicating potential for success in this approach.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Akchurin, Oleh — Weill Medical Coll of Cornell Univ
- Study coordinator: Akchurin, Oleh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.