Understanding how insecticide and drug resistance change malaria control
Official title: Understanding the Dynamics of Insecticide and Drug Resistance through Integrated Studies of Vectors, Parasites and Interventions
Funded at University of South Florida · NIH-11518530 · Data updated 2026-11-12
This grant studies how mosquitoes and malaria parasites develop resistance to insecticides and drugs, with the goal of keeping malaria prevention and treatment effective for children in Africa.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $142,400 |
| NIH project number | 3U19AI181593-03S1 |
| Project ID | NIH-11518530 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children aged 0-11 living in malaria-endemic regions or communities where resistance monitoring is being conducted.
✕Less likely to help
Communities not exposed to malaria or resistance surveillance may not directly benefit.
What this research studies
The project focuses on resistance to bed nets and indoor spraying, as well as resistance to antimalarial drugs, to protect children and other high-risk groups. It will monitor resistance in multiple sites with different transmission patterns and intervention histories. By linking resistance patterns to how malaria is controlled, the study aims to inform better, more durable prevention and treatment strategies. The work involves surveillance of vectors and parasites, plus analysis to understand how interventions influence resistance over time.
Why it matters
Potential benefit: If successful, the findings could guide improved malaria control strategies to maintain the effectiveness of nets, spraying, and drug therapies for vulnerable children.
How similar studies have gone: Previous resistance monitoring has helped adapt malaria control tools in some regions, with progressing work continuing to refine strategies.
Where this research is happening
-
University of South Florida
Tampa, United States Active
Researchers
- Principal investigator: Cui, Liwang — University of South Florida
- Study coordinator: Cui, Liwang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.