Understanding how innate lymphoid cells function and are regulated in the immune system
Elucidation of the regulation and function of innate lymphoid cells
This study is looking at special immune cells called innate lymphoid cells (ILCs) to understand how they help protect us from infections and inflammation, especially in conditions like asthma and allergies, so we can find better treatments for these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10893450 on NIH RePORTER |
What this research studies
This research investigates innate lymphoid cells (ILCs), which are important components of the immune system that help protect the body from infections and inflammation. The study focuses on how these cells are activated, migrate, and perform their immune functions, particularly in response to signals from inflamed tissues. By exploring the behavior of ILCs in various conditions, including allergic diseases and autoimmune disorders, the research aims to uncover new insights into their role in health and disease. Patients may benefit from a better understanding of how ILCs contribute to immune responses, potentially leading to new treatments for conditions like asthma and allergies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from allergic asthma or other allergic diseases.
Not a fit: Patients with non-allergic conditions or those not affected by immune system disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing allergic diseases and autoimmune disorders.
How similar studies have performed: Other research has shown promising results in understanding the role of immune cells in allergic responses, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Huang, Yuefeng — Columbia University Health Sciences
- Study coordinator: Huang, Yuefeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.