Understanding how immune cells regulate inflammation and immune responses
Deciphering the immunoregulatory network governing antigen presenting myeloid cells
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-11096046
This study is looking at how certain proteins help important immune cells, like dendritic cells and macrophages, work better in fighting inflammation and managing immune responses, which could lead to improved treatments for autoimmune diseases and other health issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11096046 on ClinicalTrials.gov |
What this research studies
This research investigates the complex networks that control the behavior of dendritic cells and macrophages, which are crucial for managing immune responses and inflammation in the body. By examining specific proteins that influence these immune cells, the study aims to uncover how they differentiate and respond to various signals. The approach involves advanced techniques like high throughput transcriptomic profiling and RNA interference to identify key genes involved in these processes. This knowledge could lead to better immunotherapies for autoimmune diseases and other conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with autoimmune conditions or those interested in the mechanisms of immune response.
Not a fit: Patients with non-autoimmune conditions or those not affected by immune system dysregulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for autoimmune diseases by enhancing our understanding of immune regulation.
How similar studies have performed: Previous research has shown promise in understanding immune cell regulation, suggesting that this approach could yield significant insights.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIPSCOMB, MICHAEL W — UNIVERSITY OF MINNESOTA
- Study coordinator: LIPSCOMB, MICHAEL W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease