Understanding how immune cells recognize each other
Molecular basis of recognition in the Immunological Synapse
This study is looking at how proteins on immune cells work together to help your body fight off diseases, with the goal of finding new ways to create treatments for autoimmune diseases and cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10820540 on NIH RePORTER |
What this research studies
This research investigates the interactions between proteins on immune cells that are crucial for the immune response. By mapping these interactions at the immune synapse, where antigen-presenting cells and T-cells communicate, the researchers aim to identify specific protein interactions that can be targeted for new treatments. The study employs a combination of computational modeling and experimental techniques to redesign protein interfaces, potentially leading to new drugs that can modulate immune responses in autoimmune diseases and cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from autoimmune diseases or specific cancers that may benefit from targeted immune therapies.
Not a fit: Patients with non-autoimmune conditions or those not affected by cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies for autoimmune diseases and certain types of cancer.
How similar studies have performed: Previous research has shown success in targeting immune interactions for therapeutic purposes, indicating that this approach has potential.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Fiser, Andras — Albert Einstein College of Medicine
- Study coordinator: Fiser, Andras
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.