Understanding how IL-2 affects immune cells that prevent autoimmune diseases
Mechanisms of regulatory T cell processes by IL-2" - TRANSFER to UNM
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · NIH-11171633
This study is looking at how a molecule called IL-2 helps special immune cells, known as regulatory T cells, stay healthy and do their job in preventing autoimmune diseases, with hopes that the results could lead to new treatments for people.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR (nih funded) |
| Locations | 1 site (ALBUQUERQUE, UNITED STATES) |
| Trial ID | NIH-11171633 on ClinicalTrials.gov |
What this research studies
This research investigates the role of IL-2, a signaling molecule, in the survival and function of regulatory T cells (Tregs), which are crucial for preventing autoimmune diseases. By using a mouse model with specific genetic modifications, the study aims to uncover how IL-2 influences Treg processes such as proliferation, metabolism, and suppressive function. The findings could lead to new therapeutic strategies for enhancing Treg function and preventing autoimmunity in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for autoimmune diseases or those with existing autoimmune conditions.
Not a fit: Patients with autoimmune diseases that are not influenced by Treg function or those without any autoimmune conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve the function of immune cells responsible for preventing autoimmune diseases.
How similar studies have performed: Other research has shown promising results in understanding Treg function and its implications for autoimmune diseases, suggesting that this approach has potential for success.
Where this research is happening
ALBUQUERQUE, UNITED STATES
- UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR — ALBUQUERQUE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHOUSE, ACACIA NICOLE — UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- Study coordinator: SHOUSE, ACACIA NICOLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases