Understanding how ICU and ward care affects patients with severe respiratory issues and sepsis

Identifying patient subgroups and processes of care that cause outcome differences following ICU vs. ward triage among patients with acute respiratory failure and sepsis

NIH-funded research University of Pennsylvania · NIH-10918227

This study looks at how choosing to treat patients with serious breathing problems and infections in either intensive care units or regular hospital rooms affects their recovery, with the aim of finding ways to improve care for these patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10918227 on NIH RePORTER

What this research studies

This research investigates how decisions to admit patients with acute respiratory failure and sepsis to either intensive care units (ICUs) or regular hospital wards impact their health outcomes. By analyzing electronic health records from millions of hospitalizations, the study aims to identify specific patient groups and care processes that lead to better or worse outcomes. The goal is to enhance patient care by understanding which factors contribute to the effectiveness of ICU versus ward treatment for these critical conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults experiencing acute respiratory failure or sepsis who are being considered for admission to either an ICU or a hospital ward.

Not a fit: Patients with stable respiratory conditions or those not requiring hospitalization may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment protocols that significantly reduce mortality rates for patients with acute respiratory failure and sepsis.

How similar studies have performed: Previous research has indicated that understanding triage decisions can lead to improved patient outcomes, suggesting that this approach has potential for success.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Respiratory Distress SyndromeAdult Respiratory Distress Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.