Understanding how hormones and sound affect hearing and communication in fish

Hormonal and acoustic regulation of the dopaminergic auditory efferent system: improving detection of social acoustic signals at the level of the inner ear

NIH-funded research Brooklyn College · NIH-10439364

This study is looking at how hormones and sounds affect hearing in fish, which might help us understand how our own hearing works, especially when it comes to social interactions and hearing loss.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionBrooklyn College NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10439364 on NIH RePORTER

What this research studies

This research investigates how hormonal and acoustic signals influence the dopaminergic system in the inner ear, particularly in the context of social communication. By studying the plainfin midshipman fish, the research aims to uncover how these signals affect auditory processing and the ability to detect social vocalizations. The study will measure changes in dopamine neurotransmission in response to hormones and characterize how social sounds can modulate dopamine synthesis. This approach could provide insights into hearing mechanisms that are relevant to humans, especially in relation to hearing loss and attention.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing hearing loss or difficulties in social communication due to auditory processing issues.

Not a fit: Patients with normal hearing and no issues related to auditory processing or communication are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of auditory processing and lead to improved treatments for hearing-related disorders.

How similar studies have performed: While this research explores novel aspects of auditory processing, similar studies have shown promising results in understanding the role of dopamine in hearing.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brain DiseasesBrain DisordersEncephalon DiseasesIntracranial CNS DisordersIntracranial Central Nervous System Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.