Understanding how hormones affect social behavior in the brain
Official title: Mapping Neural Dynamics in Hormone-sensitive Networks
Funded at Princeton University · NIH-10985545 · Data updated 2026-11-12
This study looks at how hormones related to reproduction affect our social behavior and mood, especially in people dealing with anxiety and depression, by exploring how these hormones change brain activity and gene expression.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | July 16, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $135,989 |
| NIH project number | 1K99MH135212-01A1 |
| Project ID | NIH-10985545 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing mood disorders, particularly those with anxiety or depression, who may benefit from understanding the hormonal influences on their social behaviors.
✕Less likely to help
Patients who do not have mood disorders or those whose conditions are unrelated to hormonal influences may not benefit from this research.
What this research studies
This research investigates how gonadal hormones influence social behavior by mapping neural dynamics in specific brain networks. It focuses on the interaction between hormonal states and proactive social behavior, which is crucial for mental health. By examining how these hormones affect gene expression in the brain, the study aims to uncover the underlying mechanisms that contribute to mood disorders like anxiety and depression. The research employs advanced computational methodologies to analyze the neural networks involved in social interactions.
Why it matters
Potential benefit: If successful, this research could lead to new insights into treating mood disorders by enhancing proactive social behaviors.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between hormones and social behavior, indicating that this approach has potential for significant findings.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Guthman, Eartha Mae — Princeton University
- Study coordinator: Guthman, Eartha Mae
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.