Understanding how HIV increases the risk of lung disease
Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) Study
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10448399
This study is looking at how HIV might increase the risk of lung problems like COPD by examining the immune responses and bacteria in the lungs of people with HIV, and it invites patients to help by sharing samples and information.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10448399 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between HIV infection and the increased risk of chronic obstructive pulmonary disease (COPD). It focuses on how specific immune responses and bacterial communities in the lungs contribute to lung disease in HIV-positive individuals. By analyzing microbial and genomic data, the study aims to uncover the mechanisms that lead to COPD, which is a significant health concern for those living with HIV. Patients may be involved in providing samples and data to help identify these interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for or have been diagnosed with chronic obstructive pulmonary disease.
Not a fit: Patients who do not have HIV or those without any lung disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for lung diseases in HIV-positive patients.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between microbial communities and lung diseases, indicating that this approach may yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUANG, LAURENCE — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: HUANG, LAURENCE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Chronic Disease, chronic disorder, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus